A Review of Metabolic Issues in Atypical Antipsychotic Treatment
نویسندگان
چکیده
Reports of diabetes, diabetic ketoacidosis, hyperglycemia, and dyslipidemias in patients treated with atypical antipsychotics have increased in recent years. This increase has led to growing concern about a possible link between these metabolic effects and atypical antipsychotic therapy. This review article provides an overview of the evidence for an association between glucose and lipid dysregulation and the 6 atypical antipsychotics currently available in the United States: clozapine, olanzapine, risperidone, quetiapine, ziprasidone, and aripiprazole. (Adv Stud Med. 2004;4(10H):S1045-S1058)
منابع مشابه
Effect of safranal, a constituent of saffron, on olanzapine (an atypical antipsychotic) induced metabolic disorders in rat
Objective(s): Olanzapine, an atypical antipsychotic, causes weight gain and metabolic disorders in humans. Safranal, one of the active components of Crocus sativus (saffron), has been shown to have anti-obesity, lipid and blood pressure lowering and anti-diabetes effects. In this investigation, the effect of safranal on metabolic disorders induced by olanzapine was stu...
متن کاملمقایسه مصرف آنتی‌سایکوتیک‌های تیپیک و آتیپیک در ایجاد علایم وسواسی بیماران مبتلا به اسکیزوفرنیا
AbstractObjectives: The effects of typical and atypical antipsychotics on inducing obsessive-compulsive symptoms in patients with schizophrenia were compared in this study. Method: In a comparative-descriptive study 64 patients with schizophrenia (32 patients in typical antipsychotic group and 32 patients in atypical antipsychotic group) were investigated. All patients with a confirmed diagnosi...
متن کاملDiabetic ketoacidosis associated with atypical antipsychotic drug, clozapine treatment: Report of a case and review of literature
A b st ra ct Atypical antipsychotic drugs are associated with metabolic disturbances like weight gain, type 2 diabetes hyperglycaemia and dyslipedemia, which can result in serious health risk in patients. Diabetic ketoacidosis resulting in serious metabolic acidosis, occurring in a schizophrenic patient on treatment with clozapine is being reported to draw attention this association. Frequent m...
متن کاملP-5: Evaluation of The Effect of Sulpiride As An Atypical Antipsychotic Drug, on The Serum Levels of Prolactin, LH, FSH and Testosterone in Adult Male Mice
Background: Prescription of the atypical antipsychotic drugs like as Sulpiride for the treatment of schizophrenic patients was increased because of their less side effects. This study was aimed to evaluate the effect of sulpiride on hormonal milieu of adult male mice namely their serum level of prolactin and sexual hormones. Materials and Methods: 24 adult male mice were divided in three groups...
متن کاملبررسی اثر افزودن نالترکسان به داروهای آنتی سایکوتیک، بر علایم مثبت و منفی بیماران مبتلا به اسکیزوفرنیای مزمن
Background and Purpose: In recent years, review of opioid system and its changes in the psychopathology of schizophrenia through thear probable role our on neuronal synopses and cell body of dopaminergic neurons and also decrease dopamine secretion from acumbans nuclei and effects of opium agonists in treatment of those patients has been adventajes for clinicians. Materials and methods: I...
متن کاملذخیره در منابع من
با ذخیره ی این منبع در منابع من، دسترسی به آن را برای استفاده های بعدی آسان تر کنید
عنوان ژورنال:
دوره شماره
صفحات -
تاریخ انتشار 2005